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 Message from the
Research Chair
I’m pleased to share the latest DoM research newsletter. Thank you to all the division heads and members for taking the time to provide the information that helped populate this newsletter. As always, our researchers have many achievements to celebrate and be proud of.
 

Vip Jairath
Professor, Medicine
Division of Gastroenterology
Associate Chair, Research, DOM
POEM UPDATES
New AMOSO Board Members

Two Department of Medicine faculty have been elected to the Academic Medical Organization of Southwestern Ontario for the 2026-2029 term:
  • Dr. Samuel Asfaha (Gastroenterology) elected as President.
  • Dr. George Dresser (General Internal Medicine) elected as Member.
Western Research Support Services
 
Western Research has launched two new support services:

Research Project Management - Western Research - Western University

Western Research offers centralized research project management to support funded research initiatives across Western. Our team of experienced project management professionals provide expertise in managing complex research projects and portfolios.

Institutional Research Project Managers are assigned to individual funded projects, offering tailored, project-specific support that aligns with the unique requirements of each initiative. This specialized service extends beyond the standard administrative and operational support typically available within central units, faculties, or departments.

Decision Tool for Determining Where External Grants and Contracts Are Held - Western Research - Western University
This tool is intended to be used early in the external grant or contract development process, ideally prior to submission, to help researchers determine where funding should be held. This determination is based on identifying the institution that represents the primary centre of activity, responsibility, and risk for the research.
 
PUBLICATIONS
Division of Cardiology

Al-Jarshawi M, Cole A, Bagur R, Wang HY, Ng CH, Yu D, Chew NWS, Mamas MA. Projected reduction in major adverse cardiovascular events among high-risk U.S. adults with type 2 diabetes eligible for oral semaglutide: a SOUL trial-based analysis using NHANES (1988-2018) cycles. Cardiovasc Diabetol Endocrinol Rep. 2026;12(1):33. doi: 10.1186/s40842-026-00299-z.

Dehghani P, Ellingson CJ, Singh J, Cravero E, Mancini GBJ, Stanberry L, Madan M, Benziger CP, Ghasemzadeh N, Bortnick AE, Kankaria R, Grines CL, Nayak K, Mahmud E, Bainey KR, Alraies MC, Bagai A, Patel RAG, Amlani S, Case BC, Waksman R, Shavadia JS, Stone JH, Acharya D, Javed N, Bagur R, Garberich R, Garcia S, Henry TD. Persistent one-year mortality gradient after STEMI and COVID-19: long-term outcomes from the NACMI Registry. J Soc Cardiovasc Angiogr Interv. 2026;5(8):105395.

Folleco-Insuasty L, Roa-Wandurraga LF, Liberman F, Ayan D, Bagur R, Sposato LA. Atrial fibrillation detected after stroke: Recent advances and future directions. Int J Stroke. 2026;21(7):895-901.

Kowalewska PM, Yin H, Wang M, Balint B, Hoveyda S, Manian U, Zhao PJ, Samsoondar JP, Fan KY, Nong Z, O'Neil C, Hare MTJ, Lazarte J, Goobie S, Hegele RA, Chu MWA, Pickering JG. Microfibril denudation marks early aortic vulnerability in SMAD3 variant carriers: a multigenerational study. Arterioscler Thromb Vasc Biol. 2026 Aug;46(8):e324690.
Division of Critical Care Medicine

Burns KEA, Bosma KJ, Ferreyro BL, Chaudhuri D, Seely AJE, Ouellette DR. Liberation from mechanical ventilation in acute hypoxemic respiratory failure or adult respiratory distress syndrome: a review. J Clin Med. 2026 Aug 3;15(15), 6019.

Honarmand K, Paleczny SG, Wright K, Basmaji J, Wong MY, Slessarev M, Forchuk C, Bosma KJ, Owen AM. Virtual neuropsychological assessment after severe or critical COVID-19: the NeuroCov Pilot Feasibility Study. Cureus. 2026 Apr 13;18(4):e106960.

Wang J, Russell J, Law B, Boersma D, Iansavitchene A, Laverty C, Priestap F, Smith S, Vogt K, Ball IM. Testosterone for the management of traumatic hemorrhage: a systematic review.  J Spec Oper Med. 2026 Sep 25:J.Spec.Oper.Med.2026.YT5S-X925.

Winberg C, Ball IM, Truog R. Contextualizing the dead donor rule in an era of voluntary euthanasia. NEJM. 2026 Jul 9;395(2):194-200.

Wongtirawit N, Menga LS, Brito R, Docci M, Plens GM, Alcala G, Cantan B, Bosma KJ, Ko M, Roman-Sarita G, Purcell T, Raimondi Cominesi D, Greendyk RA, Brochard L. ARDS management beyond the guidelines: a practical physiology-based approach to individualized care. Intensive Care Medicine. 2026 Sep;52(9):1910-1927.
Division of Dermatology

Kellen F, Silverman M, Shojaei E, Rahimi Shahmirzadi M, Ataie L. Pyoderma gangrenosum presenting to an infectious diseases clinic: A 2024 case series. SAGE Open Med Case Rep. 2026 Jul 26;14:2050313X261463941.
Division of Emergency Medicine

Algodi, HS, Tannar B, Suwary K, Forristal C. From forgotten experiments to global protocol: chest compressions for cardiopulmonary resuscitation (CPR) and its ‘Accidental’ rediscovery. Canadian Journal of Emergency Medicine. 2026.

Ali S, Drendel AL, Poonai N. Acetaminophen (paracetamol) or opioid plus ibuprofen for children's musculoskeletal injury-reply. JAMA. 2026 Jun 23;335(24):2167.

Buchan SA, Xie J, Bhatt M, Papenburg J, Goldfarb DM, Pernica JM, Burstein B, Gravel J, Berthelot S, Kam AJ, Poonai N, Eltorki M, Finkelstein Y, Sabhaney V, Cheng J, Gill PJ, Dickinson JA, Kwong JC, Freedman SB; SPRINT-KIDS Project Team. Respiratory syncytial virus-related hospitalizations among infants receiving nirsevimab. JAMA Netw Open. 2026 Sep 1;9(9):e2633621.

Fagnant M, Heslop CL, Chenkin J, Thavanathan R, Lalande E, Skitch S, Atkinson P, Bell CR, Myslik F, Lewis D, Jelic T, Newbigging J, Sheppard G, Olszynski P, Burwash-Brennan T, Kim DJ. POCUS literature primer: key papers on first-trimester pregnancy and scrotal POCUS.  CJEM. 2026 Jun;28(6):526-536.

Green SM, Roback MG, Bhatt M, Andolfatto G, Caperell K, Poonai N, Schwartz P, Miller JA, Wolf S, Burger RK, Sreedharan R, Vargo J, Cody P, Farmer B, Wiltz P, Suen K, Ibebuogu U, Halin N, Sherwin R, Krauss BS Unscheduled Procedural Sedation Multidisciplinary Delphi Consensus Guidelines, Part 1: Principles, Oversight, and Quality Monitoring: Approved by the ACEP Board of Directors, April 29, 2026. Ann Emerg Med. 2026 Sep;88(3):332-345.

Green SM, Roback MG, Bhatt M, Andolfatto G, Caperell K, Poonai N, Schwartz P, Miller JA, Wolf S, Burger RK, Sreedharan R, Vargo J, Cody P, Farmer B, Wiltz P, Suen K, Ibebuogu U, Halin N, Sherwin R, Krauss BS Unscheduled Procedural Sedation Multidisciplinary Delphi Consensus Guidelines, Part 2: Clinical Practice: Approved by the ACEP Board of Directors, April 29, 2026. Ann Emerg Med. 2026 Sep;88(3):346-361.

Griffiths V, Tsampalieros A, Cortel-LeBlanc A, Cortel-LeBlanc M, Greenough M, Webster RJ, Lamontagne C, Meckler G, Poonai N, Orr SL, Dodd AB, Zemek R; TRANSCENDENT Concussion Research Program. Relief and Prevention of Post-Traumatic Headache Using Intranasal Delivery of Lidocaine for Youth (RAPPIDLY): A feasibility study. Neurotrauma Rep. 2026 Aug 3;7:2689288X261470708.

Heymann EP, Romann V, Lim R, Van Aarsen K, Khatib N, Sauter T, Schild B, Mueller S. Physician wellbeing and burnout in emergency medicine in Switzerland. Swiss Med Wkly. 2024 May 16;154:3421.

Khanafer J, Doyle J, Van Aarsen K, Loosley J, Lewell M, Davis, M. Diagnosis feedback: A prospective survey on paramedic perspectives and clinical impact. International Journal of Paramedicine. 2026 Jul 15;15:113-123.

Li M, Zhong X, Goldstein J, Jensen JL, Hawco T, Carter AJE, Vanberkel P. An empirical analysis of the effect of ambulance offload delay on the efficiency of the ambulance system. Applied Sciences. 2026;16 (4): 2074. 

Mesaroli G, Hess CW, Alam F, Baker NA, Colloca L, Eccleston C, Harris L, King C, Linkiewich D, Olaizola S, Poonai N, Pope N, Rosenbloom BN, Stanton TR, Trost Z, Williams SE, Simons LE, Logan D, Stinson JN.  Development of a core outcome set for clinical trials of extended reality for pain. Pain Rep. 2026 Jul 6;11(4):e1470.

Poonai N, Kissoon N. Commentary: when less is more: reducing antibiotic overuse in immunocompetent children with febrile neutropenia. CJEM. 2026 Apr;28(4):261-262.

Yan JW, Haas NL. Managing diabetic ketoacidosis. Ann Emerg Med. 2026 Jul 2:S0196-0644(26)00365-3.
Division of Endocrinology and Metabolism

Acosta-Manzano P, Hill DJ, Leopold-Posch B, Simmons D, Devlieger R, Galjaard S, Corcoy R, Adelantado JM, Dunne F, Harreiter J, Kautzky-Willer A, Damm P, Mathiesen ER, Jensen DM, Andersen L-L, Tanvig M, Lapolla A, Dalfra M-G, Bertolotto A, Wender-Ozegowska E, Zawiejska A, Snoek FJ, Jelsma JGM, Desoye G, and van Poppel MNM. Sex-specific associations of sedentary behaviour and physical activity with placental and fetal IL-6 in pregnant women with obesity. Impact on neonatal adiposity in the DALI randomised controlled trial. Diabetes Research and Clinical Practice. 2026;237:113292.

Al-Baldawi Z, Erzingatzian A, Ruel I, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Paquette M, Baass A, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Moulson N, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Cifra B, Ransom T, McPherson R, Genest J, Brunham LR, Iatan I. Homozygous familial hypercholesterolemia (HoFH) in Canada. Atherosclerosis. 2026; 418:120792. 

Berry ASF, Cawley D, Hattenberger A, Chang AR, Hegele RA, Gidding SS, Oetjens MT. Monogenic ALB variants as determinants of severe hypercholesterolemia: A population-based cohort study. J Am Coll Cardiol. 2026 Sept 8;88(10):1093-1103.

Hang S, Hegele RA. The evaluation of plozasiran for the treatment of familial chylomicronemia syndrome. Expert Rev Endocrinol Metab. 2026; 21(3):195-204.

Hang S, Hegele RA. Clinical identification of familial chylomicronemia syndrome and novel therapeutic options. Expert Rev Cardiovas Ther. 2026;24(5):397-407.

Harreiter J, Gisinger T, Mendoza LC, Simmons D, Desoye G, Devlieger R, Galjaard S, Damm P, Mathiesen ER, Jensen DM, Andersen L-LT, Dunne F, Lapolla A, Dalfra MG, Bertolotto A, Wender-Ozegowska E, Zawiejska A, Hill DJ, Jelsma JGM, Snoek FJ, Worda C, Bancher-Todesca D, van Poppel MNM, Corcoy R, Kautzky-Willer A. Vitamin D deficiency during pregnancy is associated with greater LDL-C increase, elevated β-hydroxybutyrate, and altered neonatal metabolic markers– a secondary, pooled analysis of the randomized, controlled Vitamin D And Lifestyle for gestational diabetes prevention trial (DALI). Endocrinology, Diabetes and Metabolism. 2026 Sep;9(5):e70258.

Hegele RA. Nucleic acid-based therapies – The next frontier in treating dyslipidemias. Can J Cardiol. 2026; 42(5):1004-1017.

Hegele RA. Promise of ANGPTL3 as a therapeutic target for controlling cholesterol levels. Expert Opin Ther Targets. 2026; 30(5):463-471.

Hegele RA. Translating lipoprotein genetics into new therapies. Circ Res. 2026; 138(12):e328828.

Hegele RA. Heterozygosity for pathogenic variants in familial chylomicronemia syndrome genes: from carrier state to complex trait. Curr Opin Lipidol. 2026; 37(4):131-138.

Hegele RA. Risk-weighted apolipoprotein B: is it worth the weight? Eur Heart J. 2026; 47(26):3426-3428.

Hill DJ. Microvasculature of the pancreatic islets of Langerhans in health and diabetes. In: Handbook of Experimental Pharmacology. Eds. Centurion Pacheco, D. and Sobrevia, L. 2026. Springer, Berlin, Heidelberg. pp1-27.

Immanuel J, Chirayath S, Harreiter J, Desoye G, Corcoy R, Adelantado JM, Devlieger R, Lapolla A, Dalfra MG, Bertolotto A, Wender–Ozegowska E, Zawiejska A, Dunne FP, Damm P, Mathiesen ER, Jensen DM, Andersen LLT, Tanvig MH, Hill DJ, Jelsma JGM, Kautzky–Willer A, Galjaard S, Snoek FJ, van Poppel MNM, Simmons D. Association between relative cord hyperleptinemia and offspring outcomes in pregnant women with overweight or obesity. Pediatric Obesity. 2026 Aug;21(8):e70144.

Immanuel J, Reynolds BE, van Poppel M, Corcoy R, Andersen L-LT, Desoye G, Kautzky-Willer A, Damm P,  Harreiter J, Hill DJ, Simmons D. on behalf of the DALI investigators. Both modifiable and nonmodifiable factors are associated with small-for-gestational-age infants in mothers with overweight and obesity. Diabetes. 2026;75(Supplement 1):2617-P.
 
Joshi A, Clemens KK, Stranges S. The role of assessing frailty in cardiometabolic risk management. Nutr Metab Cardiovasc Dis. 2026 Oct;36(10):104807.
 
Kowalewska PM, Yin H, Wang M, Balint B, Hoveyda S, Manian U, Zhao PJ, Samsoondar JP, Fan KY, Nong Z, O'Neil C, Hare MTJ, Lazarte J, Goobie S, Hegele RA, Chu MWA, Pickering JG. Microfibril denudation marks early aortic vulnerability in SMAD3 variant carriers: A multigenerational study. Arterioscler Thromb Vasc Biol. 2026; 46:e324690. 
 
Nordestgaard BG, Hegele RA. Residual lipid risk in atherosclerotic cardiovascular disease. Eur Heart J. 2026; 47(26):3347-3365.

Schmidt AM, Hegele RA. Remembering Dr. Janet T. Powell. Arterioscler Thromb Vasc Biol. 2026; 45(8):1343-1345.

Schott C, Relouw S, Arnaldi M, Baker C, Offerni-Almada G, Wang J, McIntyre AD, Son S, Cuerden M, Arnold JB, Burman N, Colaiacovo S, Solo K, Boudville N, Dipchand C, Feldman LS, Gill J, Gunaratnam L, House AA, Iyer H, Johnson J, Karpinski M, Klarenbach S, Knoll G, Lok CE, Lotfy K, Miller M, Monroy-Cuadros M, Nguan C, Rehman F, Roshanov PS, Prasad GVR, Storsley L, Weir MA, Hegele RA, Garg AX, Connaughton DM. Genetic testing in kidney transplantation and living kidney donor risk assessment. Kidney Int. 2026; 110:190-205.

Thirunavukarasu BF, Kumar D, Arany E, Hill DJ. Transdifferentiation of delta- to beta-cells during normal and hyperglycemic pregnancy. Diabetes. 2026;75(Supplement 1):2953-LB.
Division of Gastroenterology

Sey M, von Renteln D, Kohansal A, Veldhuyzen van Zanten S, Singh H, Edmonds M, Wiemer H, Zhou F, Pedicelli A, Keshlaf H, Archer M, Oakland K, Guizzetti L, Barkun A, Jairath V. A national prospective multicenter comparison of risk scores against clinical judgement for the prediction of safe discharge from the emergency department in patients presenting with lower gastrointestinal bleeding. Clin Gastroenterol Hepatol. 2026 May 27:S1542-3565(26)00391-5.
Division of Hematology

Dalmia S, Hsia CC, Chin-Yee B. Clinical outcomes in triple-negative myeloproliferative neoplasms with extreme thrombocytosis: a case series. Leuk Lymphoma. 2026 Jul;67(8):1811-1815.

Del Pozzo-Magana BR, Abuzgaia AM, Fajardo RG, Wong CL, Leung S, Rieder MJ, Lazo-Langner A. A prospective cohort study of serum sickness-like reactions in the pediatric population. Paediatrics & Child Health, 2026; pxag071.

Donzel M, Khedimallah S, Barriere S, Gouband A, Aubert C, Bosselut N, Poullot E, Bezsera SM, Mansier O, Yilmaz N, Syrykh C, Hittinger X, Momenkhan S, Barraco F, Gilis L, Labussière-Wallet H, Brehon M, Chin-Yee B, Hsia C, Wang L, Zouaghi S, Sujobert P, Eveillard M, De Mas V, Tavitian S, Legros L, Parrens M, Flandrin-Gresta P, Meunier M, Freynet N, Roy L, Meignin V, Drevon L, Ranta D, Pagliuca S, Lippert E, Ianotto JC, Jallades L, Burroni B, Luque Paz D, Traverse-Glehen A, Chevalier S, Alcazer V. Prediction of bone marrow fibrosis from complete blood count in myeloproliferative neoplasms (FIBOM-AI): a multicentre machine learning model development and validation study. Lancet Haematol. 2026 Jun;13(6):e396-e407. Erratum in: Lancet Haematol. 2026 Jul;13(7):e430.

Jabbari-Zadeh F, Basharat MM, Chin-Yee B, Phua CW, Lam S, Xenocostas A, To E, Hsia CC. Acquired amegakaryocytic thrombocytopenia with evolution toward aplastic anemia treated with thrombopoietin receptor agonists: a case report. Case Rep Med. 2026 May 15;2026:6274311.

Jabbari-Zadeh F, Samuel M, Hedley B, Cabrera A, Delport J, Chin-Yee B, Hsia CC. Hematologic changes associated with measles infection: a retrospective chart review. Int J Lab Hematol. 2026 Jul 31.

Ko AK, Milana L, Riva N, Bertu L, Bertoletti L, Beyer-Westendorf J, Carrier M, Delluc A, Grandone E, Kamphuisen P, Lazo-Langner A, Maffioli M, Poli D, Schulman S, Senzolo M, Testa S, Tosetto A, Verhamme P, Leebeek FWG, Darwish Murad S, Ageno W, Lauw MN. Splanchnic vein thrombosis with and without myeloproliferative neoplasms: a comparative cohort study. J Thromb Haemost. 2026; S1538-7836(26)00337-5.

Liu J, Sadeghi S, Ho J, Mehta S, Iansavitchene A, Chin-Yee B, Hsia CC. Diagnosis, management, and outcomes of hypoxia-associated erythrocytosis. Blood Red Cells & Iron. 2026 June;2(2): 100068.

Mai V, Martens ESL, Righini M, Schulman S, Thiruganasambandamoorthy V, Bates V, Pecarskie A, Kovacs MJ, Visser S, Shivakumar S, Tan M, Rodger M, Scarvelis D, Delluc A, Girard P, Huisman MV, Wells PS, Klok FA, Le Gal G, Kahn SR; PREDICTORS study group. Patterns of presentation of suspected and confirmed recurrent venous thromboembolism in patients with prior venous thromboembolism. Res Pract Thromb Haemost. 2026;10(3):103442.

McKee A, Sadeghi S, Shao Y, Ho J, Lazo-Langner A, Chin-Yee I, Bhai P, Schenkel L, Sadikovic B, Hsia CC, Chin-Yee B. Real-world thrombotic outcomes in patients with secondary erythrocytosis in comparison with polycythemia vera. Blood Red Cells & Iron. 2026 June;2(2): 100071.

Saad M, Wang TF, Mallick R, Hill D, Lazo-Langner A, Tagalakis V, Wells PS, Carrier M. Impact of concurrent antiplatelet use on the safety and efficacy of thromboprophylaxis with apixaban in patients with cancer: A post-hoc analysis of the AVERT trial. Thromb Res. 2026;261:109681.

Shivakumar S, Matino D, Zukor D, Kahn SR, Vincent G, Mundi R, Vendittoli PA, Refaei M, Bohm E, Tanzer M, Pelet S, Richardson G, Powell J, Ikesaka R, Douketis J, Ward S, Kim P, Mann S, Pleasance S, Cormier J, Andreou P, Matheson K, Theriault C, West C, Anderson D, Gross PL; EPCAT III Trial Investigators. Rivaroxaban then aspirin vs. aspirin alone after total hip or knee arthroplasty. N Engl J Med. 2026 Jul 12.

Walker I, Deotare U, Elemary M, Elsawy M, Gallagher G, Kliman D, Panzarella T, Hamad N, Schultz KR, Storek J, Paulson K. A randomized pilot trial comparing anti-thymocyte globulin with anti-thymocyte globulin plus post transplant cyclophosphamide for prophylaxis against acute and chronic graft versus host disease in matched donor hematopoietic cell transplants – a study from the Cell Therapy Transplant Canada/ Australasian Leukemia Lymphoma Group Consortium. Bone Marrow Transplant. 2026 Aug 21.

Wang H, Kovacs MJ, Lazo-Langner A, Anderson DR, Kahn SR, Castellucci LA, Schmidt J, Elias A, Righini M, Ortel TL, Huisman MV, Carrier M, Mallick R, Rodger MA, Le Gal G, Wells PS, Xu Y. Elevated on-treatment D-dimer level is associated with major bleeding during extended anticoagulation for venous thromboembolism. Haematologica. 2026 Jul 16.
Division of Infectious Diseases

Akkielah L, Bishara A, Sowerby LJ, Johnson J, Weir MA, Chiu M, Alshafai L, Silverman M, Rahimi Shahmirzadi MR. Dual invasive fungal infections after kidney transplantation: a case report. J Fungi (Basel). 2026 Aug 19;12(8):621.

Bishara A, Saeed H, Akkielah L, BuMurah N, Driman DK, Silverman M, Rahimi Shahmirzadi R. Malakoplakia in immunocompromised hosts: a case series and literature review. Diseases. 2026 Aug 8;14(8):284.

Hill JD, Dong AHW, Liu J, Barbezani MD, Andrews TS, Klein RS. NOD2 activation reprograms infiltrating inflammatory monocytes in the Zika virus infected CNS to maintain neural correlates of learning and memory. bioRxiv. 2026 May 21.

Klein RS. The neuroimmune system and cognition. Nature Immunology. 2026 Jul;27(7):1353-1363.

Jacoby ML, Sun C, Farren JL, Marti MM, Lee AL, Donovan T, Klein RS, Rajasundaram D, Klimstra WB. Spatial dynamics of viral replication drive biphasic lymphoid activation and systemic alphavirus immune responses. PLoS Pathog. 2026 Aug 12;22(8):e1014509.
Division of Nephrology

Lanktree MB, Ashawasega N, Bevilacqua M, Bichet DG, Bollée G, Brown PA, Girard L, Goodyer P, Hingwala J, Lemaire M, McFarlane P, Moist L, Pei Y, Proulx N, Schott C, Soroka S, Vlasschaert C, Watkins N, Alam A. Canadian Society of Nephrology commentary on the 2025 Kidney Disease Improving Global Outcomes Clinical Practice Guidelines for Autosomal Dominant Polycystic Kidney Disease. Can J Kidney Health Dis. 2026 Jun 3;13:20543581261455635.

Quinn RR, Oliver MJ, Wald R, Hiremath S, Pauly RP, Miller L, Barrett B, Nesrallah G, Gallagher M, Kotwal S, Gray NA, Hassan HC, Talaulikar GS, Thorpe K, Graham J, Clarke A, Bian J, MacRae J, Santana M, Bohm C, Mamdani M, Nagpal S, Yilmaz S, Moist L, Ravani P. Comparing catheters to fistulas in older patients starting hemodialysis: A pilot randomized controlled trial. J Am Soc Nephrol. 2026 Jun 22.
Division of Respirology

Hansen S, Tsai MJ, Tran TN, Blakey JD, Emmanuel B, Aaron SD, Habis Y, Perugini V, Altraja A, Katial RK, Perez-de-Llano L, Pfeffer PE, Papadopoulos NG, Townend J, Scelo G, Beastall A, Bulathsinhala L, Busby J, Lindsley AW, Moore WC, Panettieri RA Jr, Canonica GW, Heffler E, Cardini C, Guida G, Porsbjerg CM, Bjerrum AS, Von Bülow A, Hilberg O, Håkansson KEJ, Soendergaard MB, Ulrik CS, Wang E, Wechsler ME, Chapman N, Hoyte FCL, Otsu K, Heaney LG, Jackson DJ, Patel PH, Ryan D, Bergeron C, Abercromby S, Bhutani M, Chapman KR, Côté A, Davis BE, Dorscheid DR, Hoshyari L, Philipenko B, Serajeddini H, Schleich F, Louis R, Kuna P, Cosio BG, Larenas-Linnemann D, Torres-Duque CA, Fernández-Sánchez MJ, Garcia E, Bolívar-Grimaldos F, Jiménez-Maldonado L, Cano-Rosales DJ, Solarte I, Al-Lehebi R, Bulkhi AA, Al-Ahmad M, Iwanaga T, Hozawa S, Matsumoto H, Nagano T, Tajiri T, Aarli BB, Perng DW, Hsiao YH, Fu PK, Sheu CC, Kostikas K, Gaga M, Gogali A, Kallieri M, Loukides S, Makris M, Ntakoula MD, Papaioannou AI, Paraskevopoulos G, Psarros F, Mahboub B, Salameh L, Koh MS, Liew MF, Pang PH, Tan TL, Tay TR, Pitrez PM, Rhee CK, Lugogo N, Mohan A, Fonseca JA, da Silva AA, Loureiro CC, Dos Santos HCAS, Máspero JF, Ardusso LRF, Franchi ME, Sivori M, Stok AM, Yañez A, Christoff G, Popov TA, Mitchell PD, Salvi SS, Costello RW, Denton E, Hew M, Jenkins CR, Langton D, Middleton PG, Peters MJ, Lehtimäki L, Bourdin A, Taillé C, Taube C, Csoma Z, Lúdvíksdóttir D, van Boven JFM, Fingleton J, Bjermer L, Emery H, Lough G, Pleasants RA, Maselli DJ, Ambrose CS, Emmas C, Menzies-Gow AN, Carter V, Eleangovan N, Murray RB, Price CA, Sadatsafavi M, Price DB; ISAR GLEAM Working Group; ISAR GLEAM Working Group; List of ISAR collaborators; List of CHRONICLE collaborators; ISAR GLEAM Working Group; List of ISAR collaborators; List of CHRONICLE collaborators. Association of easier biologic access with remission and other clinical outcomes in severe asthma: a global real-world study. J Asthma Allergy. 2026 Aug 6;19:597657.

Canonica GW, Christoff GC, Tsai MJ, Tran TN, Townend J, Scelo G, Beastall A, Bulathsinhala L, Busby J, Lindsley AW, Moore WC, Panettieri RA Jr, Heffler E, Cardini C, Guida G, Wang E, Wechsler ME, Chapman N, Hoyte F, Katial RK, Otsu K, Porsbjerg CM, Bjerrum AS, von Bülow A, Hansen S, Hilberg O, Julius Håkansson KE, Søndergaard MB, Ulrik CS, Heaney LG, Jackson DJ, Patel PH, Pfeffer PE, Ryan D, Kuna P, Bergeron C, Aaron SD, Abercromby S, Bhutani M, Chapman KR, Côté A, Davis BE, Dorscheid DR, Hoshyari L, Philipenko B, Sadatsafavi M, Serajeddini H, Larenas-Linnemann D, Cosio BG, Perez-de-Llano L, Torres-Duque CA, Fernández-Sánchez MJ, Garcia E, Bolívar-Grimaldos F, Jiménez-Maldonado L, Cano-Rosales DJ, Solarte I, Schleich F, Louis R, Al-Lehebi R, Bulkhi AA, Habis Y, Al-Ahmad M, Mahboub B, Salameh L, Pitrez PM, Iwanaga T, Hozawa S, Matsumoto H, Nagano T, Tajiri T, Fonseca JA, Alves da Silva A, Loureiro CC, Cristhina de Azevedo Soares Dos Santos H, Papadopoulos NG, Kostikas K, Gaga M, Gogali A, Kallieri M, Loukides S, Makris M, Ntakoula M, Papaioannou AI, Paraskevopoulos G, Psarros F, Perng DW, Hsiao YH, Fu PK, Sheu CC, Aarli BB, Popov TA, Koh MS, Liew MF, Pang PH, Lee Tan T, Tay TR, Rhee CK, Máspero J, Ardusso LRF, Franchi ME, Sivori M, Stok AM, Yañez A, Lugogo N, Mohan A, Mitchell PD, Altraja A, Salvi S, Costello RW, Denton EJ, Hew M, Jenkins C, Langton D, Middleton PG, Peters MJ, Lehtimäki L, Bourdin A, Taillé C, Taube C, Csoma Z, Lúdvíksdóttir D, van Boven JFM, Fingleton J, Emery H, Lough G, Perugini V, Bjermer L, Maselli DJ, Pleasants RA, Ambrose CS, Emmanuel B, Emmas C, Menzies-Gow AN, Parulekar AD, Carter V, Eleangovan N, Murray RB, Price CA, Blakey JD, Price DB; ISAR GLEAM Working Group. Assessing the impact of earlier initiation of biologics on clinical remission and other outcomes in a global real-life severe asthma cohort from CHRONICLE, ISAR and OPCRD. Chest. 2026 Sep 9:S0012-3692(26)06552-9.
GRANTS
Division of Cardiology

Rodrigo Bagur, co-applicant
Nominated Principal Applicant: PJ Devereaux
Principal Applicants: Guy Rouleau, Alexander Lim, Emilie Belley-Cote
Accelerating Clinical Trials-2 (ACT-2)
CIHR Accelerating Clinical Trials Canada Consortium Grant
$23,350,000 (3 years)
Division of Endocrinology and Metabolism

Kristin Clemens, co-principal investigator
Principal Investigator: Van Lu
Co-Principal Investigators:Pin C, Clemens KK, Asfaha S
Novel mechanisms to release an endogenous reservoir of GLP-1 in the human colon
CIHR
$1,355,000
Division of Gastroenterology

Samuel Asfaha, principal investigator
Co-Principal Investigator: John Ronald
Cell-intrinsic regulation of colorectal cancer stem cells by transposable element-driven viral mimicry
CIHR Project Grant
$1,078,000 (5 years) 
Division of General Internal Medicine

Jacquline Torti
(In)Visible contributions in grant capture: a critical exploratory study of professional research staff's experiences and the structures that shape them
2026 SSHRC Insight Development Grant
$69,000
Division of Geriatric Medicine

Manuel Montero-Odasso, co-applicant
Using circulating microglia extracellular vesicles to discriminate microglia activation phenotype, and cognitive outcomes in comorbid AD and stroke
CIHR
$1,227,826 (5 years)
Division of Hematology

Alejandro Lazo-Langner, co-investigator
Enabling and Engaging patients to DECIDE indefinite versus short-term anticoagulation for VTE (DECIDE-VTE): a stepped-wedge cluster randomized trial
CIHR
$589,052
Division of Infectious Diseases

Robyn S. Klein, principal investigator
Sex differences in neurocognitive recovery from West Nile virus neuroinvasive disease
CIHR
$1,395,000 (5 years)
 
MohammadReza Rahimi Shahmirzadi, principal investigator
Prospective evaluation of a structured anal cancer screening program for solid organ transplant recipients: a single-centre cohort study at the London Health Sciences Centre
Spring 2026 IRF competition
$20,000
Division of Nephrology

Louise Moist, co-investigator
Satisfaction in Hemodialysis Patients On ShoWERing With CVCs and Healed Exit Sites: the
SHOWER study
CIHR Project Grant
$711,451 
Division of Physiology and Pharmacology

Tom Appleton, co-applicant
Ectopic calcification of spinal tissues: leveraging preclinical mouse models and patient samples to investigate therapeutic targets for diffuse idiopathic skeletal hyperostosis (DISH)
CIHR
$837,676 (5 years)
Division of Respirology

Hana Serajeddini, principal investigator
SARRECOMS study: Sustained Asthma Remission and Reduced RElapse using a COmprehensive Management Strategy Randomized Control Trial
AMOSO Innovation
$64,808
Division of Rheumatology

Janet Pope (principal investigator), Lillian Barra (co-applicant)
AI-assisted multimodal imaging for joint damage assessment, flare prediction, and personalized management of rheumatoid arthritis
CIHR
$1,154,386 (5 years)
APPOINTMENTS AND AWARDS
Division of Cardiology
 
Rodrigo Bagur
EuroIntervention Journal annual editorial board and award ceremony, Best Editor Award
Division of Endocrinology and Metabolism
 
Robert Hegele
Induction into the Canadian Medical Hall of Fame in Calgary, June 18, 2026
Division of Geriatric Medicine
 
Manuel Montero-Odasso
Leaders Circle Recognition Award, City of Toronto program to recognize local leaders who bring major international meetings to the city
IN THE NEWS
Division of Endocrinology and Metabolism

Kristin Clemens
What’s New in Osteoporosis
Good Times, June 24, 2026
Division of Gastroenterology

Michael Sey
Oakland score a ‘useful tool’ for predicting safe discharge in lower GI bleeding
Healio, July 13, 2026
 
Oakland score showed highest specificity for safe discharge in lower GI bleeding
GI & Hepatology News, June 18, 2026
Division of Infectious Diseases

Robyn Klein
New CIHR funding brings $14.3M to health researchers at Schulich, hospitals
Schulich School of Medicine and Dentistry News, July 28, 2026
Division of Nephrology

Kayla Naylor
Researcher finds gender gap in kidney transplant referrals
Schulich School of Medicine & Dentistry News, June 15, 2026
PRESENTATIONS
Division of Cardiology

Mosa Abbadi (Interventional Fellow), Rodrigo Bagur (supervisor)
Optimizing Patient Trajectory to improve comprehensive assessment of coronary artery disease in TAVI
EuroPCR 2026, Paris, France, May 2026
 
Federico Liberman (Interventional Fellow), Rodrigo Bagur (supervisor)
Sex differences in coronary assessment before TAVI: insights from OPTICS-CAD study
EuroPCR 2026, Paris, France, May 2026
 
Rodrigo Bagur
Code stroke following cardiac catheterization procedures: contrast induced encephalopathy vs stroke
EuroPCR 2026, Paris, France, May 2026
Division of Dermatology

R. Fajardo, Lili Ataie (supervisor)
Hyperhomocysteinemia and cutaneous phenotypes in chronic venous leg ulcers: a systematic review (poster)
Canadian Dermatology Association Conference, Calgary, Alberta, June 25, 2026
Division of Endocrinology and Metabolism

Robert Hegele
Lipodystrophy (invited lecture)
AMBQ/CAMB Annual Meeting, Saint-Sauveur, QC (via WebEx), May 28, 2026
 
Robert Hegele
Early LDL-C reduction in cardiovascular risk management: why timing matters (invited lecture, Amgen speaking engagement)
London, ON, May 4, 2026
 
Robert Hegele
Clinical advances in CV risk reduction for patients with dyslipidemia (invited lecture, HLS speaking engagement)
London, ON, May 26, 2026
 
Robert Hegele
What’s new in lipids?
Department of Medicine Medical Grand Rounds, University Hospital, London, ON, May 29, 2026
 
Robert Hegele
Lipid physiology for clinicians
Endocrine Summer Series Rounds, University Hospital, London, ON, July 22, 2026
Division of Hematology

Alejandro Lazo-Langner (moderator)
How to manage patients with cerebral and retinal vein thrombosis
34th Congress of the International Society on Thrombosis and Haemostasis 2026, Paris, France, July 11-15
Division of Infectious Diseases

Robyn Klein
Emerging RNA viruses and cognition (seminar speaker)
Department of Microbiology & Immunology, Dartmouth College, Hanover, NH, May 11, 2026
 
Robyn Klein
Virus-mediated cognitive impairment (keynote speaker)
1st International Workshop on Virus & Brain, Montpellier, France, June 4, 2026
 
Robyn Klein
Host-pathogen neuroimmunology gone wrong: orthoflaviviruses and cognitive decline (Organizer, invited speaker)
Keystone Symposia on Neurodegenerative Diseases and Neuroimmune Interactions, Whistler, BC, June 22, 2026
Division of Respirology

Hana Serajeddini
Understanding the limitations of fractional exhaled nitric oxide as a longitudinal predictor for remission in patients with moderate to severe asthma while on biologic therapy
ERS Congress, Sept. 7, 2026
MEMBER UPDATES
Centre for Education Research & Innovation

Lorelei Lingard
Elected Fellow of the Royal Society of Canada 
Division of Gastroenterology

Samuel Asfaha
Appointed inaugural Verspeeten Chair in Translational Cancer Research 

Vipul Jairath
Re-appointed as the Dr. John W.D. and Susan McDonald Chair in Inflammatory Bowel Disease at the Schulich School of Medicine & Dentistry, Western University, effective February 1, 2026 to January 31, 2031
 
Division of General Internal Medicine

Mark Goldszmidt
Appointed Director of the Centre for Education Research and Innovation (CERI) for a five-year term, effective June 1, 2026, transitioning from his current role as Interim Director
Division of Nephrology

Amit Garg
Re-appointed as the Associate Dean, Clinical Research, at the Schulich School of Medicine & Dentistry, Western University effective October 1, 2026, to September 30, 2031

Lakshman Gunaratnam
Re-appointed the Dr. Robert Zhong Chair in Translational Transplant Research, effective April 1, 2026, to March 31, 2031
Copyright ©2026 Program of Experimental Medicine, Schulich School of Medicine and Dentistry.
All rights reserved.


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