| Nephrology Peter.Blake@lhsc.on.ca |
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 PETER BLAKE, MD, FRCPC, FRCPI, MB, MSc (Hons), ProfessorDr. Peter Blake is a Professor of Medicine in the Division of Nephrology at the University of Western Ontario and London Health Sciences Centre in London, Ontario. Over the past two decades, Dr. Blake has published over 100 papers in the area of peritoneal dialysis and adequacy of dialysis in general. He has been Editor of two major textbooks in Nephrology. He has served as Editor-in-Chief since 2001 of Peritoneal Dialysis International. He is or has been a member of the Editorial Boards of the Journal of the American Society of Nephrology, the American Journal of Nephrology, Advances in Renal Replacement Therapy, and Nephrology News and Issues. He has given over 200 invited talks in 25 different countries. Dr. Blake has served on the National Kidney Foundation K/DOQI Peritoneal Dialysis Work Group, and the International Society of Peritoneal Dialysis Council (ISPD). He has been Chair of the Canadian Society of Nephrology Work Group on Peritoneal Dialysis since 1998 and has Co-Chaired the International Society of Nephrology (ISN) North American Task Force on Renal Disasters on behalf of the ISN Acute Renal Failure Commission. In 2013, he was appointed Provincial Medical Director of the Ontario Renal Network (ORN), the agency that administers renal services in Ontario. Dr. Blake graduated from University College Dublin Medical School in 1980. He received his Masters degree in Immunology from the University of Alberta in 1992. He also holds the FRCPC, Royal College of Physicians of Canada and the FRCPI, Royal College of Physicians of Ireland. Keywords: Dialysis delivery systems internationally Dialysis dose: Optimization of with particular regard to peritoneal dialysis Dialysis patients: Malnutrition Dialysis patients: Registry studies Dialysis: Economics Dialysis: Prescription and adequacy (Major Focus) Hemodialysis: Recirculation and urea rebound Peritoneal dialysis prescriptions: Patient compliance Peritoneal dialysis: Determinants of outcome in patients | |||
| Nephrology Michael.Chiu@lhsc.on.ca |
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 MICHAEL CHIU, MD, FRCPC, Assistant ProfessorDr. Michael Chiu is a Nephrologist and an Assistant Professor with the Department of Medicine, Division of Nephrology, at the University of Western Ontario. He completed his nephrology training in 2019 at the University of Western Ontario along with subspecialty training in home dialysis in 2020. Over this time, Dr. Chiu also completed a Masters of Science in Healthcare Quality through Queens University in 2020. Dr. Chiu’s research interests are in Chronic Kidney Disease, Home Dialysis, and Quality Improvement. Keywords: Chronic Kidney Disease Home Dialysis Quality Improvement | |||
| Nephrology Dervla.Connaughton@lhsc.on.ca |
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 Dr. Dervla Connaughton, MD, PhD, Assistant Professor of MedicineDr. Dervla Connaughton is an Assistant Professor of Medicine in the Division of Nephrology at Western University and currently is the inaugural Eugen Drewlo Chair for Kidney Research and Innovation at the Schulich School of Medicine & Dentistry. She received her medical degree and specialist training from the Royal College of Surgeons in Ireland and completed a transplant fellowship at the National Centre for Nephrology and Transplantation at Beaumont Hospital in Ireland. She was awarded her PhD degree from Trinity College Dublin in renal genetics and a Master’s of Science in Epidemiology from the London School of Hygiene and Tropical Medicine. She also completed a fellow fellowship at Harvard University and Boston Children's Hospital where she carried out genetic research investigating monogenic causes of chronic kidney disease in both adult and pediatric populations. The main focus of research is on understanding the genetic basis and epidemiology of all forms of chronic kidney disease. Specifically, her focus is to establish and characterize the molecular etiology in genetic kidney disease using high throughput sequencing techniques including gene panel sequencing, whole exome and genome sequencing. Dr. Connaughton joined the nephrology division at LHSC in October 2019. She cares for patients with glomerulonephritis, those that require hemodialysis, patients undergoing kidney transplant as well as patient wishing to donate a kidney through the live donation process. She has set up a specialist clinic for the evaluation of patients and their families who may have a genetic form of kidney disease. Keywords: Familial nephropathy Genetics Glomerulonephritis Home hemodialysis Kidney diseases Monogenic disease Next generation sequencing Transplantation Whole exome sequencing | |||
| Nephrology andrea1.cowan@lhsc.on.ca |
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| ANDREA COWAN, MD, FRCPC, Assistant Professor Bio sketch and keywords unavailable. | |||
| Nephrology Amit.Garg@lhsc.on.ca |
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 AMIT GARG, MD, FRCPC, FACP, MEd, PhD, Professor Dr. Amit Garg is Professor of Medicine - Division of Nephrology and of Epidemiology and Biostatistics at Western University. He is the Associate Dean of Clinical Research for the Schulich School of Medicine and Dentistry and is Lead of the ICES Provincial Program focused on Kidney, Dialysis and Transplantation Research (ICES KDT). He is a Scientist at the Lawson Health Research Institute and at ICES, and an Associate Scientist at the Population Health Research Institute. He is the past medical director of the living kidney donor program at the London Health Sciences Centre, a past president of the Canadian Society of Nephrology, the past Director of the Institute for Clinical Evaluative Sciences (ICES) Western Facility, and the past Medical Lead, Access to Kidney Transplantation for the Ontario Renal Network. Characterized by his peers as a world-class clinical and health services investigator in kidney, dialysis and transplantation medicine, Dr. Garg feels most fortunate to be able to contribute in this way and is grateful to be supported and surrounded by so many brilliant people, both in the workplace and at home. Working in teams, he has over 600 published articles with more than 1,000 different authors from over 50 international centres (h-index 112). The research has appeared in top medical journals and in the lay press including CTV, Global News, and the New York Times. It has been widely acknowledged for helping understand how different treatments alter the risk of acute kidney injury from elective surgery, improving the practice and safety of living kidney donation, and reducing adverse events from prescription medications. Additionally, the research has made it easier for fellow researchers and clinicians to systematically search for relevant kidney-related content in large bibliographic databases thanks to the development of specialized filters, and to conduct large-scale randomized trials using streamlined methods. Dr. Garg has mentored and trained future researchers. He has been the primary research supervisor to over 75 trainees at Western University from who he has learned a great deal. He is also grateful to work with a team of highly qualified research administrators, coordinators, data managers, epidemiologists and statisticians in London, Ontario. In 2021 Dr. Garg was awarded the Hellmuth Prize, Western University's highest distinction for sustained excellence in research, and the Kidney Foundation of Canada Medal for Research Excellence. In 2016 he received the Donald W. Seldin Young Investigator Award from the American Society of Nephrology, which is presented annually to one individual with an outstanding record of achievement and creativity in basic or patient-orientated research related to the functions and diseases of the kidney. Keywords: Clinical trials Dialysis Epidemiology Health Informatics Health Services Research Healthcare Databases Kidney diseases Medical education Meta-analysis Observational studies using administrative databases Systematic reviews Transplantation | |||
| Nephrology Lakshman.Gunaratnam@lhsc.on.ca |
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 LAKSHMAN GUNARATNAM, MD, FRCPC, Associate Professor Dr. Gunaratnam is a nephrologist and Associate Professor of Medicine at Western University. He currently holds the Dr. Robert Zhang Chair in Translational Transplant Research at Western and is Medical Director of Multi-Organ Transplant Program at the London Health Sciences Center. Dr. Gunaratnam completed his undergraduate and graduate studies at the University of Toronto in immunology and then went on to attend medical school and complete residency training in internal medicine at the University of Ottawa. Dr. Gunaratnam completed research fellowships at the University of Ottawa (Dr. Stephen Lee) and Harvard Medical School (Dr. Joseph V. Bonventre) in cancer biology and acute kidney injury, respectively. After completing his clinical fellowship in nephrology at the Massachusetts General Hospital and Brigham and Women’s Hospital in 2009, he did additional training in renal transplantation with Dr. Anil Chandraker at Brigham and Women’s Hospital. He was promoted to Instructor in Medicine at Harvard Medical School and later served as an associate physician at Brigham and Women’s Hospital prior to moving to London, Ontario. Dr. Gunaratnam leads a basic and translational research program focused on the biological mechanisms underlying acute kidney injury, prolonging the lifespan of kidney transplants, and novel treatments for kidney cancer. His research program is supported by peer-reviewed funding from several agencies including the Canadian Institutes for Health Research, the Kidney Foundation of Canada, the Natural Sciences and Engineering Research Council of Canada, the Government of Ontario, and the Canadian Foundation for Innovation. He holds several advisory and leadership positions in Canadian medical organizations, including, Canadian Blood Services, Trillium Gift of Life Network, Canadian Society of Transplantation, and the Ontario Medical Association. Keywords: Acute kidney injury Cell death Cell signalling G proteins Inflammation Ischemia-reperfusion injury Kidney Injury Molecule-1 Phagocytosis Protein tyrosine phosphorylation | |||
| Nephrology Andrew.House@lhsc.on.ca |
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 ANDREW HOUSE, MD, FRCPC, HBSc, MSc, Professor, Chair, Division of Nephrology Dr. Andrew House is a Professor in the Faculty of Medicine at the Schulich School of Medicine & Dentistry, Western University, and is currently the Chair of the Western University Division of Nephrology. He did his training in Physiology & Pharmacology at Western before his MD and specialist training at the University of Ottawa, and Masters in Epidemiology & Biostatistics at Western. As a trained clinical epidemiologist and nephrologist, Dr. House focuses on the design and analysis of clinical trials in AKI, CKD, hemodialysis and transplantation. In 2007 he completed a six month sabbatical in Vicenza, Italy, where he developed expertise in Critical Care Nephrology and Cardiorenal Syndromes. He collaborates on research into drug metabolism in varying degrees of chronic kidney disease. He was a member of the ADQI consensus conferences on Cardio-Renal Syndromes held in Venice in 2008 and 2012, and was a Distinguished Faculty at a symposium on Cardio-Renal Syndromes at the American Society of Nephrology Annual Meeting in San Diego, 2009, a symposium on Heart Failure Syndromes at the American Thoracic Society Annual Meeting in New Orleans, 2010, and the Vicenza Course on Hemodialysis in Vicenza, Italy, 2011. He was co-Chair of the international KDIGO Conference on Congestive Heart Failure in May 2017, and invited lecturer on Heart Failure in Chronic Kidney Disease at the 7th Annual Nephrology Summit in Kochin and Hyderabad, India in September 2017. More recently, he helped establish the Adult Tuberous Sclerosis Clinic at LHSC, which he directs, and has turned his research sites on understanding mechanisms and treatments for this complex syndrome. Keywords: Cardio-renal syndromes Cardiovascular disease Clinical trials Hemodialysis Homocysteine Kidney diseases Transplantation Tuberous Sclerosis Complex | |||
| Nephrology susan.huang@lhsc.on.ca |
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 SHIH-HAN SUSAN HUANG, MD, FRCPC, Associate Professor
I have completed my medical degree at the University of Ottawa in 2005 and finished the specialty/subspecialty trainings (internal medicine and nephrology) in 2010 at Western University. In addition, I have successfully completed the Certificate in the Department of Epidemiology and Biostatistics in 2012. In 2015, I received my PhD degree through the Department of Medical Biophysics with the support of numerous research awards, including the Canadian Institute of Health Research (CIHR) Fellowship Award for Health Professional and the Vanier CGS award. My doctoral research was on dialysis adequacy using a new marker, cystatin C. I currently have over 50 publications and over 10 research projects ongoing. My research interests include medical biophysics, TTP and extracoporeal therapies. Keywords: Cystatin C Glomerular nephritis Hemodialysis Plasmapheresis | |||
| Nephrology Arsh.Jain@lhsc.on.ca |
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 ARSH JAIN, MD, FRCPC, Associate ProfessorDr. Arsh Jain is an Assistant Professor of Medicine at the University of Western Ontario. He is a practicing Nephrologist at the London Health Sciences Centre and his clinical expertise is in the area of Peritoneal Dialysis. Dr. Jain conducts clinical and health services research to improve health outcomes for patients with kidney diseases. Keywords: Chronic kidney disease Epidemiology Internal Medicine Nephrology Peritoneal dialysis Time Series Analysis | |||
| Nephrology john.johnson@lhsc.on.ca |
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 JOHN JOHNSON, BSc, MD, MSc, MHPE, FRCPC, Associate Professor
Associate Professor of Medicine, Division of Nephrology Site Chief, Division of Nephrology, University Hospital Program Director, Nephrology Transplant Fellowship Associate Program Director, Nephrology Residency Co-Chair, Epidemiology Course, Undergraduate Medical Education, Schulich School of Medicine and Dentistry, Western University London Health Sciences Centre, London, Ontario, Canada (Ph) 519-663-3319 (Fax) 519-663-3449 Keywords: Peritoneal dialysis Renal Transplantation | |||
| Nephrology christopher.mcintyre@lhsc.on.ca |
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 CHRIS MCINTYRE, MD, PhD, FRCPC, Professor
Dr. McIntyre is Professor of Medicine, Professor of Medical Biophysics, Professor of Paediatrics and Robert Lindsay Chair of Dialysis Research and Innovation at Western. He also serves as Director of the Lilibeth Caberto Kidney Clinical Research Unit at London Health Sciences Centre, where he is also a practicing Clinical Nephrologist. He leads a team of multidisciplinary researchers focused largely on the pathophysiology of the effecting cardiovascular, brain, liver and gastro-intestinal structure and function in patients with chronic kidney disease. These studies include basic clinical science, natural history studies and the development and application of novel therapeutic strategies into large scale randomized controlled trials. These studies have increasingly focused on the adverse consequences resulting from dialysis therapy itself and the improvement in outcomes by the reduction of preventable harm. Multimodal imaging plays an important role in these studies including ultrasound, CT, PET and MRI. Keywords: Applied Imaging Cardio Renal Medicine Chronic Kidney Disease Hemodialysis Peritoneal Dialysis | |||
| Nephrology louise.moist@lhsc.on.ca |
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 LOUISE MOIST, MD, FRCPC, MSc, Professor Dr. Moist is a Clinician Researcher and Professor of Medicine and Epidemiology and Biostatistics at the University of Western Ontario and Associate Chair, Division of Nephrology at the London Health Sciences Centre. Dr. Moist is a Certified Canadian Physician Executive, credentialing her significant role in healthcare leadership. Dr. Moist is clinically active in both inpatient and outpatient settings and teaches students and residents at all levels of training including supervision of students completing a Masters in Epidemiology and Biostatistics. Dr. Moist is Associate Director of the Center for Quality Innovation and Safety, Department of Medicine Western University. She is leading the first community antibiotic stewardship initiative for Ontario West and leads the discharge timeliness improvement project at LHSC. Dr. Moist is developing further knowledge in translation science and collaborative research. Dr. Moist research interests include progression and treatment of chronic kidney disease (CKD), Obesity in CKD and vascular access, with a focus on implementation science. Dr. Moist has received peer-reviewed research funding from multiple sources including CIHR and Kidney Foundation of Canada, Her publications include over 250 peer reviewed papers Dr. Moist has received a number of awards including e the Canadian Society of Nephrology Distinguished Service Award, MAC Chairs Award for outstanding contribution to quality improvement and patient safety Schulich School of Medicine & Dentistry Dean’s Award of Excellence in Undergraduate Education and an Award of Excellence in Research. Dr. Moist is recognized each year for her mentorship and leadership within the academic environment. Keywords: Chronic kidney disease Diabetes Myelitis Dialysis Epidemiology Health Care Outcomes Health systems leadership Hemodialysis Knowledge translation Obesity Prevention Quality Improvement Vascular access | |||
| Nephrology Pavel.Roshanov@lhsc.on.ca |
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| PAVEL ROSHANOV, MD, FRCPC, Assistant Professor Bio sketch unavailable at this time. | |||
| Nephrology mweir@uwo.ca |
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 MATTHEW WEIR, MD, FRCPC, MSc, Associate ProfessorDr. Weir is a nephrologist at the London Health Sciences Centre and the Medical Director of the Kidney Care Centre. He treats patients with chronic kidney disease including those who require dialysis or transplantation. His research interests relate to the interactions between pharmaceutics, impaired renal function and hemodialysis. Dr. Weir is honoured to be a part of the multidisciplinary team at the Kidney Clinical Research Unit where he seeks to generate new knowledge that will improve the health of patients suffering with kidney disease. Keywords: Renal Pharmacoepidemiology Drug Safety | |||
| Nephrology zhuxu.zhang@lhsc.on.ca |
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 ZHU-XU ZHANG, PHD, Associate Professor
Dr. Zhang graduated at Zhongshan University in China and late received his PhD degree from Karolinska Institute, Sweden in 1997. He finished his postdoctoral training in the Department of Pathology, University of Toronto in 2003. He is currently a professor in the Department of Medicine and the Department of Pathology at Western University. His laboratory is at the Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre. His research interest is focused on the mechanisms of immune regulation and tolerance. He and his colleagues have identified a novel type of regulatory T cells, double negative (DN-Treg) cells, that can suppress immune responses and prolong graft survival. In addition, his team has found that NK cells can mediate ischemia reperfusion injury and chronic rejection in transplantation. Recently, Dr. Zhang and colleagues were the first to describe the contribution of necroptosis in transplantation. Currently, there are two areas under active investigation in his laboratory: i) the mechanism of cell death pathways-mediated tissue injury and its effects on permitting tolerance induction in transplantation, and ii) the role of NK and T cells in immune tolerance. He is a member of AST, CST and AAI. His research has been supported by CIHR, CDTRP, HSF and KFOC. Keywords: Apoptosis Kidney injury Necroptosis NK cell Regulatory T cell Transplantation | |||
