Program of Experimental Medicine - POEM
Department of Medicine

Program of Experimental Medicine
POEM


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Nephrology
ARSH JAIN, MD, FRCPC, Associate Professor

Dr. Arsh Jain is an Assistant Professor of Medicine at the University of Western Ontario. He is a practicing Nephrologist at the London Health Sciences Centre and his clinical expertise is in the area of Peritoneal Dialysis. Dr. Jain conducts clinical and health services research to improve health outcomes for patients with kidney diseases.

Keywords:
Chronic kidney disease
Epidemiology
Internal Medicine
Nephrology
Peritoneal dialysis
Time Series Analysis


Gastroenterology
VIPUL JAIRATH, MD, FRCPC, Associate Professor

Dr. Vipul Jairath is a gastroenterologist, specializing in the management of Crohn’s disease, ulcerative colitis, endoscopy and a range of general gastrointestinal disorders. He trained in the United Kingdom and has degrees in pharmacology and medicine from the University of Leeds, a PhD (DPhil) from the University of Oxford and diploma in clinical trials from the London School of Hygiene and Tropical Medicine.

He joined Western University in 2016 as Associate Professor of Medicine, Epidemiology and Biostatistics, and is the recipient of John and Susan Mcdonald endowed chair.

His research interests are in the design, conduct and implementation of randomized controlled trials, index development and outcomes research. He has received peer reviewed grant funding from several organizations and supervises students both at masters and doctoral level.

Keywords:
Clinical trials-Design and execution
Gastrointestinal Bleeding
IBD
Index development
Outcomes research
Trial design and mythology


Clinical Immunology and Allergy
SAMIRA JEIMY, MD, PhD, FRCPC, ABIM Assistant Professor

Dr. Jeimy completed medical school and internal medicine residency at the University of Toronto, followed by clinical immunology and allergy fellowship at Western University. She completed PhD studies in platelet immunology at McMaster University, supported by a Canadian Institutes of Health Research (CIHR) Banting and Best Doctoral Award. She is board certified in internal medicine (FRCPC, ABIM), and in clinical immunology and allergy (FRCPC). She is an assistant professor at Western University and the Program Director for Clinical Immunology and Allergy at Western University.

Her research interests include food and drug allergy, and she engages in multi-centre research from colleagues across the country. She is a co-chair of the scientific sessions committee at the Canadian Society of Allergy and Clinical Immunology. Her medical advocacy efforts include allergy education through social media (@allergies_explained on instagram; @drsamirajeimy on X) and collaborations including with the “Focused COVID Communications” group, which creates decision aids, clinical tools, and infographics. She is the OMA Women committee chair, OMA Allergy section Vice-Chair, and Women in Allergy and Immunology c-chair.

Keywords:
Anaphylaxis
Biologic therapies
Chronic urticaria
Food and drug allergies
Hereditary angioedema


Nephrology
ANTHONY JEVNIKAR, MD, FRCPC, Professor

Dr. Jevnikar completed undergraduate and graduate programs in Microbiology and Immunology from The University of Western Ontario and received his MD from the Schulich School of Medicine in 1981. He received further research training in transplant and renal molecular immunology at the Brigham and Women’s Hospital in Boston before returning to Canada in 1991. He is a transplant nephrologist, professor of Medicine, Surgery, and Microbiology & Immunology, Medical Director of Kidney Transplantation and Co-Director of the Multi Organ Transplant Program at University Hospital in London, Ontario. He founded and is currently the Scientific Director of the Matthew Mailing Centre for Translational Transplant Studies at LHRI.

Dr. Jevnikar is a clinician-scientist with a strong focus on translational research as well as patient care. His research has been continuously supported since 1988 by the Kidney Foundation of Canada and the Canadian Institutes of Health Research (CIHR), and the NIH for tolerance work in non-human primates. He has authored or co-authored more than 170 original research publications on both basic and clinical research primarily in transplantation, but also Type I diabetes. In addition to his basic research in epithelial cell injury and the regulation of cellular death by endogenous inhibitors of programmed cell death as a means to promote allograft survival, he also developed other novel research program such as the creation and use of genetically altered plants expressing human proteins to produce biotherapeutics such as cytokines that cannot be practically produced in the quantities required for clinical applications by any other system. He is a strong advocate for the role of clinician-scientists in medical research. He has received awards in recognition of his research contributions, including the Kidney Foundation of Canada Medal for Research Excellence in 2005, the Wyeth-CIHR Chair in Clinical Transplantation in 2008, the Faculty Scholar Award by the Schulich School of Medicine and Dentistry in 2011, and Lifetime Achievement Awards from the Canadian Society of Transplantation (2015) and the Schulich School of Medicine and Dentistry (2016).

Dr. Jevnikar has been an active member of both the Canadian Society of Transplantation (CST) and American Society of Transplantation (AST). Having gone from Council and Executive Board, he went on to become President of the Canadian Society of Transplantation from 2002-04. In the AST, he has served on the Board and many important committees including the co-chair of the Education Committee (2005-2007). He has organized many national and international meetings including the AST Fellows Meeting, American Transplant Congress (Chair 2009 - 2010), the AST 'Cutting Edge of Transplant (CEOT)' annual meeting and most recently the Ontario Transplant Forum (2015). He is the past Chair of the Advisory Board of the Canadian Institute of Health for Infection and Immunity (2009-2016) which covered transplantation and autoimmunity research in Canada.

Keywords:
Apoptosis
Apoptosis, Necrosis and cell death
Caspase regulation
Cytokines
Epithelial Cell
Immune biomarkers
Immunosuppression
Inflammation
Ischemia
Kidney
Kidney and tissue injury
Mouse models
Necroptosis
Organ preservation
Reperfusion
Transplant immunobiology
Transplantation


Nephrology
JOHN JOHNSON, BSc, MD, MSc, MHPE, FRCPC, Associate Professor

Associate Professor of Medicine, Division of Nephrology
Site Chief, Division of Nephrology, University Hospital
Program Director, Nephrology Transplant Fellowship
Associate Program Director, Nephrology Residency
Co-Chair, Epidemiology Course, Undergraduate Medical Education, Schulich School of Medicine and Dentistry, Western University
London Health Sciences Centre, London, Ontario, Canada
(Ph) 519-663-3319 (Fax) 519-663-3449

Keywords:
Peritoneal dialysis
Renal Transplantation


Endocrinology and Metabolism
TISHA JOY, MD, FRCPC, Associate Professor

Dr. Joy received her medical degree from the Western University, Canada in 2001. After completing residency training at Western University in 2006, she went on to be a research fellow specializing in HIV lipodystrophy at Massachusetts General Hospital (Harvard Medical School) in Boston, MA. Upon completion of this in 2007, she pursued another research fellowship in genetic lipodystrophies and dyslipidemia at Robarts Research Institute, London, ON, until 2008. She is an Associate Professor in the Division of Endocrinology and Metabolism at Western University and Associate Scientist in the Lawson Health Research Institute. Her research interests include type 2 diabetes, obesity, and lipid disorders, including statin-associated muscle symptoms and has published several articles in these areas. She has been invited as a guest speaker for the Meet the Professor/Meet the Expert sessions at the American Heart Association and Endocrine Society conferences. She also has collaborated on research initiatives related to equity, diversity, and inclusion. She has a Diversity and Inclusion Certificate from Cornell in 2021, and is the Equity, Diversity, Inclusion and Belonging Lead for the Department of Medicine (2023 to present).

Keywords:
Body fat distribution
Equity, diversity, and inclusion
Lipid disorders
Obesity
Statin myopathy
statin-associated muscle symptoms
Type 2 diabetes